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An inorganic compound with the chemical formula As2O3 that is used for the treatment of ACUTE PROMYELOCYTIC LEUKEMIA in patients who have relapsed from, or are resistant to, conventional drug therapy. NCI: A small-molecule arsenic compound with antineoplastic activity. The mechanism of action of arsenic trioxide is not completely understood. Arsenic trioxide is the inorganic compound with the formula As 2 O 3.

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The arsenic is in its +3 oxidation state. Mol. formula: As2O3 Hazard classification & labelling Hazard classification and labelling The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. Injection: 12 mg/6 mL (2 mg/mL) arsenic trioxide in single-dose vial. (3) CONTRAINDICATIONS Hypersensitivity to arsenic. (4) WARNINGS AND PRECAUTIONS • Hepatotoxicity: Elevated aspartate aminotransferase (AST), alkaline phosphatase and serum bilirubin have occurred in patients with newly-diagnosed low-risk APL treated with TRISENOX Arsenic Trioxide - 5 - Section 11 - Toxicological Information RTECS: CAS# 1327-53-3: CG3325000 LD50/LC50: CAS# 1327-53-3: Oral, mouse: LD50 = 20 mg/kg; Oral, rabbit: LD50 = 20190 ug/kg; Oral, rat: LD50 = 10 mg/kg Carcinogenicity: CAS# 1327-53-3: ACGIH: A1 - Confirmed Human Carcinogen (listed as 'Arsenic, inorganic compounds'). 2020-09-18 · QT c (Framingham formula) prolongation >450 msec (for males) or >460 msec (for females): Withhold arsenic trioxide and any medication known to prolong the QTc interval. Replete electrolytes.

The mechanism of action of arsenic trioxide is not completely understood.

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Data Zone | Discovery | Facts | Appearance & Characteristics | Uses | Abundance & Isotopes | References. 33. Арсенов триоксид је неорганско једињење чија је хемијска формула Ас2О3. Арсен се у свом металном стању брзо трансформише у овај оксид, који је  arsenic(III) oxide; arsenic trioxide.

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An inorganic compound with the chemical formula As2O3 that is used for the treatment of ACUTE PROMYELOCYTIC LEUKEMIA in patients who have relapsed from, or are resistant to, conventional drug therapy. NCI: A small-molecule arsenic compound with antineoplastic activity. The mechanism of action of arsenic trioxide is not completely understood.

This produces toxic fumes of arsenic oxides.
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H20 arsenous oxide data sheet, from the Compendium of Pesticide Common Names, including IUPAC and CAS systematic names, molecular formula, structural formula, CAS Registry Number and InChI. CAS name: arsenic oxide (As2O3). Arsenic Trioxide (Trisenox) chemotherapy side effects, how it's given, how it works, precautions and self care tips in treatment of acute promyelocytic leukemia. 28 Mar 2018 Arsenic Trioxide Genetic Information.

The arsenic removed by roasting is mixed in the dust ash. Objective Intravenous arsenic trioxide (ATO) and all-trans retinoic acid have become the front-line treatments for patients with acute promyelocytic leukemia (APL).
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CAS no.: 1327-53-3. Mol. formula: As2O3. formula diarsenic trioxide; arsenic trioxide. An industrially important oxide of arsenic that occurs as the mineral claudetite; formula As2O3 (though in liquid, gaseous and some solid forms it has molecules  APL0406 study proves that ATRA plus arsenic trioxide is at least not inferior and may be Arm Group-etikett: Oral Realgar-Indigo naturalis formula(RIF) Group. In this study, the investigators evaluate the use of oral-As2O3 and ATRA based Frontline Oral Arsenic Trioxide-based Induction in Newly Diagnosed Acute Glomerular filtration rate (GRF) by Cockcroft-Gault formula or eGFR (MDRD) of less  Definition av arsenic trioxide.

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As a medication, it is used to treat a type of cancer known as acute promyelocytic leukemia. For this use it is given by injection into a vein. Arsenic trioxide has the formula As2O3. B , 2019 , 7 , 3088. Arsenic trioxide, sold under the brand name Trisenox among others, is an inorganic compound and medication. As a medication, it is used to treat a type of cancer known as acute … FORMULA: As 2 O 3 (As 4 O 6) MOL WT. 197.84: H.S. CODE.

As2O3  Molar mass of As2O3 = 197.8414 g/mol.